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Alexander Leithner
Alexander Leithner
Dirección de correo verificada de kennedy.ox.ac.uk
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Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice
M Brown, FP Assen, A Leithner, J Abe, H Schachner, G Asfour, ...
Science 359 (6382), 1408-1411, 2018
3852018
Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes
A Leithner, A Eichner, J Müller, A Reversat, M Brown, J Schwarz, J Merrin, ...
Nature cell biology 18 (11), 1253-1259, 2016
1712016
Chemokines and integrins independently tune actin flow and substrate friction during intranodal migration of T cells
M Hons, A Kopf, R Hauschild, A Leithner, F Gaertner, J Abe, J Renkawitz, ...
Nature immunology 19 (6), 606-616, 2018
1122018
Locally triggered release of the chemokine CCL21 promotes dendritic cell transmigration across lymphatic endothelia
K Vaahtomeri, M Brown, R Hauschild, I De Vries, AF Leithner, M Mehling, ...
Cell reports 19 (5), 902-909, 2017
902017
Dendritic cells interpret haptotactic chemokine gradients in a manner governed by signal-to-noise ratio and dependent on GRK6
J Schwarz, V Bierbaum, K Vaahtomeri, R Hauschild, M Brown, I De Vries, ...
Current Biology 27 (9), 1314-1325, 2017
682017
WASp triggers mechanosensitive actin patches to facilitate immune cell migration in dense tissues
F Gaertner, P Reis-Rodrigues, I De Vries, M Hons, J Aguilera, M Riedl, ...
Developmental cell 57 (1), 47-62. e9, 2022
642022
Dendritic cell actin dynamics control contact duration and priming efficiency at the immunological synapse
A Leithner, LM Altenburger, R Hauschild, FP Assen, K Rottner, ...
Journal of Cell Biology 220 (4), e202006081, 2021
392021
Fast and efficient genetic engineering of hematopoietic precursor cells for the study of dendritic cell migration
AF Leithner, J Renkawitz, I De Vries, R Hauschild, H Häcker, MK Sixt
European journal of immunology 48 (6), 2018
372018
Micro-engineered “pillar forests” to study cell migration in complex but controlled 3D environments
J Renkawitz, A Reversat, A Leithner, J Merrin, M Sixt
Methods in cell biology 147, 79-91, 2018
212018
Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14
K Tomasek, A Leithner, I Glatzova, MS Lukesch, CC Guet, M Sixt
Elife 11, e78995, 2022
102022
Geometrically complex microfluidic devices for the study of cell migration
A Leithner, J Merrin, A Reversat, M Sixt
Protoc. Exch 10, 2016
62016
Mechanosensitivity of amoeboid cells crawling in 3D
F Gaertner, P Reis-Rodrigues, I de Vries, M Hons, J Aguilera, M Riedl, ...
BioRxiv, 2021.05. 11.443058, 2021
52021
Solution structure and synaptic analyses reveal molecular mechanisms of bispecific T cell engagers
O Staufer, A Leithner, F Liberta, S Zhou, F Schiele, S Reindl, H Nar, ...
bioRxiv, 2022.06. 15.496334, 2022
12022
Segmental flexibility of bispecific T-cell engagers regulates the dynamics of immune synapse formation
O Staufer, A Leithner, S Zhou, M Crames, S Comeau, D Young, S Low, ...
12022
A resource for extracellular vesicles from activated CD4 T cells that relay pro-inflammatory signals
AK Jainarayanan, RS Mahla, J Capera, M Elanchezhian, D Gupta, ...
bioRxiv, 2024.10. 15.618584, 2024
2024
En-Face Imaging of T Cell-Dendritic Cell Immunological Synapses
A Leithner, J Merrin, M Sixt
The Immune Synapse: Methods and Protocols, 137-147, 2023
2023
Solution structure and synaptic analyses reveal determinants of bispecific T cell engager potency
A Leithner, O Staufer, T Mitra, F Liberta, S Valvo, M Kutuzov, H Dada, ...
bioRxiv, 2022.06. 15.496334, 2022
2022
A supported lipid bilayer platform to study the impact of bi-specific engager architecture on T cell activation
A Leithner, S Kasturirangan, ML Dustin
European Journal of Immunology 51 (S1), 2021
2021
Geometrically complex microfluidic devices for the study of cell migration
M Sixt, A Leithner, J Merrin, A Reversat
2016
The muscle specific transcriptome of Nematostella vectensis
A Leithner
na, 2012
2012
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Artículos 1–20