Jacob F. Kocher
Jacob F. Kocher
Director of Virology
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MERS-CoV accessory ORFs play key role for infection and pathogenesis
VD Menachery, HD Mitchell, AS Cockrell, LE Gralinski, BL Yount Jr, ...
MBio 8 (4), 10.1128/mbio. 00665-17, 2017
High dose and low dose Lactobacillus acidophilus exerted differential immune modulating effects on T cell immune responses induced by an oral human rotavirus vaccine in …
K Wen, G Li, T Bui, F Liu, Y Li, J Kocher, L Lin, X Yang, L Yuan
Vaccine 30 (6), 1198-1207, 2012
Allelic Variation in the Toll-Like Receptor Adaptor Protein Ticam2 Contributes to SARS-Coronavirus Pathogenesis in Mice
LE Gralinski, VD Menachery, AP Morgan, AL Totura, A Beall, J Kocher, ...
G3: Genes, Genomes, Genetics 7 (6), 1653-1663, 2017
High protective efficacy of rice bran against human rotavirus diarrhea via enhancing probiotic growth, gut barrier function and innate immunity
X Yang, E Twitchell, G Li, K Wen, M Weiss, J Kocher, S Lei, A Ramesh, ...
Scientific reports 5 (1), 15004, 2015
Probiotic Lactobacillus rhamnosus GG enhanced Th1 cellular immunity but did not affect antibody responses in a human gut microbiota transplanted neonatal gnotobiotic pig model
K Wen, C Tin, H Wang, X Yang, G Li, E Giri-Rachman, J Kocher, T Bui, ...
PloS one 9 (4), e94504, 2014
Hypergraph models of biological networks to identify genes critical to pathogenic viral response
S Feng, E Heath, B Jefferson, C Joslyn, H Kvinge, HD Mitchell, ...
BMC bioinformatics 22 (1), 287, 2021
Lactobacillus rhamnosus GG on rotavirus-induced injury of ileal epithelium in gnotobiotic pigs
F Liu, G Li, K Wen, S Wu, Y Zhang, T Bui, X Yang, J Kocher, J Sun, ...
Journal of pediatric gastroenterology and nutrition 57 (6), 750-758, 2013
High protective efficacy of probiotics and rice bran against human norovirus infection and diarrhea in gnotobiotic pigs
S Lei, A Ramesh, E Twitchell, K Wen, T Bui, M Weiss, X Yang, J Kocher, ...
Frontiers in microbiology 7, 1699, 2016
Intranasal P particle vaccine provided partial cross-variant protection against human GII. 4 norovirus diarrhea in gnotobiotic pigs
J Kocher, T Bui, E Giri-Rachman, K Wen, G Li, X Yang, F Liu, M Tan, ...
Journal of virology 88 (17), 9728-9743, 2014
Probiotics and virulent human rotavirus modulate the transplanted human gut microbiota in gnotobiotic pigs
H Zhang, H Wang, M Shepherd, K Wen, G Li, X Yang, J Kocher, ...
Gut pathogens 6 (1), 39, 2014
Median infectious dose of human norovirus GII. 4 in gnotobiotic pigs is decreased by simvastatin treatment and increased by age
T Bui, J Kocher, Y Li, K Wen, G Li, F Liu, X Yang, T LeRoith, M Tan, M Xia, ...
Journal of General Virology 94 (9), 2005-2016, 2013
Adaptive evolution influences the infectious dose of MERS-CoV necessary to achieve severe respiratory disease
MG Douglas, JF Kocher, T Scobey, RS Baric, AS Cockrell
Virology 517, 98-107, 2018
Lactobacillus rhamnosus GG modulates innate signaling pathway and cytokine responses to rotavirus vaccine in intestinal mononuclear cells of gnotobiotic pigs transplanted with …
H Wang, K Gao, K Wen, IC Allen, G Li, W Zhang, J Kocher, X Yang, ...
BMC microbiology 16 (1), 109, 2016
Lactobacillus rhamnosus GG dosage affects the adjuvanticity and protection against rotavirus diarrhea in gnotobiotic pigs
K Wen, F Liu, G Li, M Bai, J Kocher, X Yang, H Wang, S Clark-Deener, ...
Journal of pediatric gastroenterology and nutrition 60 (6), 834-843, 2015
Probiotic Lactobacillus rhamnosus GG mono-association suppresses human rotavirus-induced autophagy in the gnotobiotic piglet intestine
S Wu, L Yuan, Y Zhang, F Liu, G Li, K Wen, J Kocher, X Yang, J Sun
Gut pathogens 5 (1), 22, 2013
Dietary rice bran protects against rotavirus diarrhea and promotes Th1-type immune responses to human rotavirus vaccine in gnotobiotic pigs
X Yang, K Wen, C Tin, G Li, H Wang, J Kocher, K Pelzer, E Ryan, L Yuan
Clinical and Vaccine Immunology 21 (10), 1396-1403, 2014
Dual functions of Lactobacillus acidophilus NCFM as protection against rotavirus diarrhea
F Liu, K Wen, G Li, X Yang, J Kocher, T Bui, D Jones, K Pelzer, ...
Journal of pediatric gastroenterology and nutrition 58 (2), 169-176, 2014
Characterization of immune modulating functions of γδ T cell subsets in a gnotobiotic pig model of human rotavirus infection
K Wen, T Bui, G Li, F Liu, Y Li, J Kocher, L Yuan
Comparative immunology, microbiology and infectious diseases 35 (4), 289-301, 2012
Norovirus vaccines and potential antinorovirus drugs: recent advances and future perspectives
J Kocher, L Yuan
Future virology 10 (7), 899-913, 2015
Emergence of novel human norovirus GII. 17 strains correlates with changes in blockade antibody epitopes
LC Lindesmith, JF Kocher, EF Donaldson, K Debbink, ML Mallory, ...
The Journal of Infectious Diseases 216 (10), 1227-1234, 2017
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