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David Brealey
David Brealey
Consultant Intensive Care Medicine, University College Hospital
Verified email at doctors.org.uk
Title
Cited by
Cited by
Year
Association between mitochondrial dysfunction and severity and outcome of septic shock
D Brealey, M Brand, I Hargreaves, S Heales, J Land, R Smolenski, ...
The Lancet 360 (9328), 219-223, 2002
17492002
Preliminary UK experience of dexmedetomidine, a novel agent for postoperative sedation in the intensive care unit
RM Venn, CJ Bradshaw, R Spencer, D Brealey, E Caudwell, C Naughton, ...
Anaesthesia 54 (12), 1136-1142, 1999
7931999
Mapping the human genetic architecture of COVID-19
Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ...
Nature 600 (7889), 472-477, 2021
7512021
Mitochondrial dysfunction in a long-term rodent model of sepsis and organ failure
D Brealey, S Karyampudi, TS Jacques, M Novelli, R Stidwill, V Taylor, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2004
5832004
Levosimendan for the prevention of acute organ dysfunction in sepsis
AC Gordon, GD Perkins, M Singer, DF McAuley, RML Orme, ...
New England Journal of Medicine 375 (17), 1638-1648, 2016
3352016
Preoperative intravenous iron to treat anaemia before major abdominal surgery (PREVENTT): a randomised, double-blind, controlled trial
T Richards, RR Baikady, B Clevenger, A Butcher, S Abeysiri, M Chau, ...
The Lancet 396 (10259), 1353-1361, 2020
2732020
Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study
RK Gupta, EM Harrison, A Ho, AB Docherty, SR Knight, M van Smeden, ...
The Lancet Respiratory Medicine 9 (4), 349-359, 2021
2242021
Prevalence of phenotypes of acute respiratory distress syndrome in critically ill patients with COVID-19: a prospective observational study
P Sinha, CS Calfee, S Cherian, D Brealey, S Cutler, C King, C Killick, ...
The Lancet Respiratory Medicine 8 (12), 1209-1218, 2020
2192020
Rapid diagnosis of infection in the critically ill, a multicenter study of molecular detection in bloodstream infections, pneumonia, and sterile site infections
JL Vincent, D Brealey, N Libert, NE Abidi, M O’Dwyer, K Zacharowski, ...
Critical care medicine 43 (11), 2283-2291, 2015
1922015
Mitochondrial dysfunction in sepsis
D Brealey, M Singer
Current infectious disease reports 5 (5), 365-371, 2003
1852003
Mitochondrial dysfunction in sepsis
M Singer, D Brealey
Biochemical Society Symposia 66, 149-166, 1999
1811999
Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the …
CI Bloom, TM Drake, AB Docherty, BJ Lipworth, SL Johnston, ...
The Lancet Respiratory Medicine 9 (7), 699-711, 2021
1712021
Effect of human recombinant alkaline phosphatase on 7-day creatinine clearance in patients with sepsis-associated acute kidney injury: a randomized clinical trial
P Pickkers, RL Mehta, PT Murray, M Joannidis, BA Molitoris, JA Kellum, ...
Jama 320 (19), 1998-2009, 2018
1592018
Effect of lower tidal volume ventilation facilitated by extracorporeal carbon dioxide removal vs standard care ventilation on 90-day mortality in patients with acute hypoxemic …
JJ McNamee, MA Gillies, NA Barrett, GD Perkins, W Tunnicliffe, D Young, ...
Jama 326 (11), 1013-1023, 2021
1492021
Hyperglycemia in critical illness: a review
D Brealey, M Singer
Journal of diabetes science and technology 3 (6), 1250-1260, 2009
1492009
Effect of intravenous interferon β-1a on death and days free from mechanical ventilation among patients with moderate to severe acute respiratory distress syndrome: a …
VM Ranieri, V Pettilä, MK Karvonen, J Jalkanen, P Nightingale, D Brealey, ...
Jama 323 (8), 725-733, 2020
1372020
Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind …
T Welte, RP Dellinger, H Ebelt, M Ferrer, SM Opal, M Singer, JL Vincent, ...
Intensive care medicine 44, 438-448, 2018
1272018
Mitochondrial dysfunction in patients with severe sepsis: an EPR interrogation of individual respiratory chain components
DA Svistunenko, N Davies, D Brealey, M Singer, CE Cooper
Biochimica Et Biophysica Acta (BBA)-Bioenergetics 1757 (4), 262-272, 2006
1262006
Evidence for chemokine synergy during neutrophil migration in ARDS
AE Williams, RJ José, PF Mercer, D Brealey, D Parekh, DR Thickett, ...
Thorax 72 (1), 66-73, 2017
1132017
Effect of intermittent or continuous feed on muscle wasting in critical illness: a phase 2 clinical trial
AS McNelly, DE Bear, BA Connolly, G Arbane, L Allum, A Tarbhai, ...
Chest 158 (1), 183-194, 2020
1122020
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