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Izhar Karbat
Izhar Karbat
Research associate, Dept. of biological chemistry, The Weizamann Institute, Rehovot, Israel
Verified email at weizmann.ac.il - Homepage
Title
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Cited by
Year
The insecticidal potential of scorpion β-toxins
M Gurevitz, I Karbat, L Cohen, N Ilan, R Kahn, M Turkov, M Stankiewicz, ...
Toxicon 49 (4), 473-489, 2007
1532007
The differential preference of scorpion α-toxins for insect or mammalian sodium channels: Implications for improved insect control
D Gordon, I Karbat, N Ilan, L Cohen, R Kahn, N Gilles, K Dong, ...
Toxicon 49 (4), 452-472, 2007
1322007
Common features in the functional surface of scorpion β-toxins and elements that confer specificity for insect and mammalian voltage-gated sodium channels
L Cohen, I Karbat, N Gilles, N Ilan, M Benveniste, D Gordon, M Gurevitz
Journal of Biological Chemistry 280 (6), 5045-5053, 2005
1152005
Molecular basis of the high insecticidal potency of scorpion α-toxins
I Karbat, F Frolow, O Froy, N Gilles, L Cohen, M Turkov, D Gordon, ...
Journal of Biological Chemistry 279 (30), 31679-31686, 2004
1152004
Structure-function map of the receptor site for β-scorpion toxins in domain II of voltage-gated sodium channels
JZ Zhang, V Yarov-Yarovoy, T Scheuer, I Karbat, L Cohen, D Gordon, ...
Journal of Biological Chemistry 286 (38), 33641-33651, 2011
892011
Dissection of the functional surface of an anti-insect excitatory toxin illuminates a putative “hot spot” common to all scorpion β-toxins affecting Na+ channels
L Cohen, I Karbat, N Gilles, O Froy, G Corzo, R Angelovici, D Gordon, ...
Journal of Biological Chemistry 279 (9), 8206-8211, 2004
832004
Mapping the interaction site for a β-scorpion toxin in the pore module of domain III of voltage-gated Na+ channels
JZ Zhang, V Yarov-Yarovoy, T Scheuer, I Karbat, L Cohen, D Gordon, ...
Journal of Biological Chemistry 287 (36), 30719-30728, 2012
742012
Molecular requirements for recognition of brain voltage-gated sodium channels by scorpion α-toxins
R Kahn, I Karbat, N Ilan, L Cohen, S Sokolov, WA Catterall, D Gordon, ...
Journal of biological chemistry 284 (31), 20684-20691, 2009
692009
An ‘Old World’scorpion β‐toxin that recognizes both insect and mammalian sodium channels: A possible link towards diversification of β‐toxins
D Gordon, N Ilan, N Zilberberg, N Gilles, D Urbach, L Cohen, I Karbat, ...
European journal of biochemistry 270 (12), 2663-2670, 2003
642003
X-ray structure and mutagenesis of the scorpion depressant toxin LqhIT2 reveals key determinants crucial for activity and anti-insect selectivity
I Karbat, M Turkov, L Cohen, R Kahn, D Gordon, M Gurevitz, F Frolow
Journal of molecular biology 366 (2), 586-601, 2007
592007
The unique pharmacology of the scorpion α‐like toxin Lqh3 is associated with its flexible C‐tail
I Karbat, R Kahn, L Cohen, N Ilan, N Gilles, G Corzo, O Froy, M Gur, ...
The FEBS journal 274 (8), 1918-1931, 2007
572007
Molecular analysis of the sea anemone toxin Av3 reveals selectivity to insects and demonstrates the heterogeneity of receptor site-3 on voltage-gated Na+ channels
Y Moran, R Kahn, L Cohen, M Gur, I Karbat, D Gordon, M Gurevitz
Biochemical Journal 406 (1), 41-48, 2007
522007
Elucidation of the molecular basis of selective recognition uncovers the interaction site for the core domain of scorpion α-toxins on sodium channels
M Gur, R Kahn, I Karbat, N Regev, J Wang, WA Catterall, D Gordon, ...
Journal of Biological Chemistry 286 (40), 35209-35217, 2011
512011
A spider toxin that induces a typical effect of scorpion α-toxins but competes with β-toxins on binding to insect sodium channels
G Corzo, P Escoubas, E Villegas, I Karbat, D Gordon, M Gurevitz, ...
Biochemistry 44 (5), 1542-1549, 2005
502005
Deletion of PsbM in tobacco alters the QB site properties and the electron flow within photosystem II
P Umate, S Schwenkert, I Karbat, C Dal Bosco, L Mlcochova, S Volz, ...
Journal of biological chemistry 282 (13), 9758-9767, 2007
492007
Modern venomics—Current insights, novel methods, and future perspectives in biological and applied animal venom research
BM von Reumont, G Anderluh, A Antunes, N Ayvazyan, D Beis, ...
GigaScience 11, 2022
422022
Expression and mutagenesis of the sea anemone toxin Av2 reveals key amino acid residues important for activity on voltage-gated sodium channels
Y Moran, L Cohen, R Kahn, I Karbat, D Gordon, M Gurevitz
Biochemistry 45 (29), 8864-8873, 2006
402006
Variations in receptor site‐3 on rat brain and insect sodium channels highlighted by binding of a funnel‐web spider δ‐atracotoxin
N Gilles, G Harrison, I Karbat, M Gurevitz, GM Nicholson, D Gordon
European journal of biochemistry 269 (5), 1500-1510, 2002
372002
Direct evidence that receptor site-4 of sodium channel gating modifiers is not dipped in the phospholipid bilayer of neuronal membranes
L Cohen, N Gilles, I Karbat, N Ilan, D Gordon, M Gurevitz
Journal of biological chemistry 281 (30), 20673-20679, 2006
362006
Partial agonist and antagonist activities of a mutant scorpion β-toxin on sodium channels
I Karbat, N Ilan, JZ Zhang, L Cohen, R Kahn, M Benveniste, T Scheuer, ...
Journal of biological chemistry 285 (40), 30531-30538, 2010
212010
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