An integrated encyclopedia of DNA elements in the human genome ENCODE Project Consortium Nature 489 (7414), 57, 2012 | 17346 | 2012 |
Comprehensive Identification of Cell Cycle–regulated Genes of the Yeast Saccharomyces cerevisiae by Microarray Hybridization PT Spellman, G Sherlock, MQ Zhang, VR Iyer, K Anders, MB Eisen, ... Molecular biology of the cell 9 (12), 3273-3297, 1998 | 6549 | 1998 |
Exploring the metabolic and genetic control of gene expression on a genomic scale JL DeRisi, VR Iyer, PO Brown Science 278 (5338), 680-686, 1997 | 6364 | 1997 |
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project Management Group Liefer Laura A. 51 Wetterstrand Kris A. 51 Good Peter J. 51 ... nature 447 (7146), 799-816, 2007 | 6124 | 2007 |
The accessible chromatin landscape of the human genome RE Thurman, E Rynes, R Humbert, J Vierstra, MT Maurano, E Haugen, ... Nature 489 (7414), 75-82, 2012 | 3189 | 2012 |
Systematic variation in gene expression patterns in human cancer cell lines DT Ross, U Scherf, MB Eisen, CM Perou, C Rees, P Spellman, V Iyer, ... Nature genetics 24 (3), 227-235, 2000 | 2756 | 2000 |
The transcriptional program in the response of human fibroblasts to serum VR Iyer, MB Eisen, DT Ross, G Schuler, T Moore, JCF Lee, JM Trent, ... science 283 (5398), 83-87, 1999 | 2648 | 1999 |
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia SG Landt, GK Marinov, A Kundaje, P Kheradpour, F Pauli, S Batzoglou, ... Genome research 22 (9), 1813-1831, 2012 | 2339 | 2012 |
Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF VR Iyer, CE Horak, CS Scafe, D Botstein, M Snyder, PO Brown Nature 409 (6819), 533-538, 2001 | 1448 | 2001 |
FAIRE (Formaldehyde-Assisted Isolation of Regulatory Elements) isolates active regulatory elements from human chromatin PG Giresi, J Kim, RM McDaniell, VR Iyer, JD Lieb Genome research 17 (6), 877-885, 2007 | 1199 | 2007 |
Drug target validation and identification of secondary drug target effects using DNA microarrays MJ Marton, JL DeRisi, HA Bennett, VR Iyer, MR Meyer, CJ Roberts, ... Nature medicine 4 (11), 1293-1301, 1998 | 928 | 1998 |
A user's guide to the encyclopedia of DNA elements (ENCODE) RM Myers, J Stamatoyannopoulos, M Snyder, I Dunham, RC Hardison, ... PLoS biology 9 (4), 2011 | 683 | 2011 |
Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity L Song, Z Zhang, LL Grasfeder, AP Boyle, PG Giresi, BK Lee, ... Genome research 21 (10), 1757-1767, 2011 | 639 | 2011 |
Whole-genome expression analysis of snf/swi mutants of Saccharomyces cerevisiae P Sudarsanam, VR Iyer, PO Brown, F Winston Proceedings of the National Academy of Sciences 97 (7), 3364-3369, 2000 | 557 | 2000 |
Genome-wide analysis of the biology of stress responses through heat shock transcription factor JS Hahn, Z Hu, DJ Thiele, VR Iyer Molecular and cellular biology 24 (12), 5249-5256, 2004 | 521 | 2004 |
Dynamic remodeling of individual nucleosomes across a eukaryotic genome in response to transcriptional perturbation S Shivaswamy, A Bhinge, Y Zhao, S Jones, M Hirst, VR Iyer PLoS biology 6 (3), e65, 2008 | 520 | 2008 |
Poly (dA: dT), a ubiquitous promoter element that stimulates transcription via its intrinsic DNA structure. V Iyer, K Struhl The EMBO journal 14 (11), 2570-2579, 1995 | 514 | 1995 |
Genetic reconstruction of a functional transcriptional regulatory network Z Hu, PJ Killion, VR Iyer Nature genetics 39 (5), 683-687, 2007 | 507 | 2007 |
High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells AP Boyle, L Song, BK Lee, D London, D Keefe, E Birney, VR Iyer, ... Genome research 21 (3), 456-464, 2011 | 422 | 2011 |
Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis MK Mulligan, I Ponomarev, RJ Hitzemann, JK Belknap, B Tabakoff, ... Proceedings of the National Academy of Sciences 103 (16), 6368-6373, 2006 | 402 | 2006 |