Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis S Sawcer, G Hellenthal, M Pirinen, CCA Spencer, NA Patsopoulos, ... Nature 476 (7359), 214, 2011 | 3050 | 2011 |
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations JZ Liu, S Van Sommeren, H Huang, SC Ng, R Alberts, A Takahashi, ... Nature genetics 47 (9), 979-986, 2015 | 2664 | 2015 |
Risk alleles for multiple sclerosis identified by a genomewide study International Multiple Sclerosis Genetics Consortium New England Journal of Medicine 357 (9), 851-862, 2007 | 2122 | 2007 |
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis AH Beecham, NA Patsopoulos, DK Xifara, MF Davis, A Kemppinen, ... Nature genetics 45 (11), 1353, 2013 | 1374 | 2013 |
The “All of Us” research program All of Us Research Program Investigators New England Journal of Medicine 381 (7), 668-676, 2019 | 1289 | 2019 |
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility International Multiple Sclerosis Genetics Consortium*†, ANZgene, ... Science 365 (6460), eaav7188, 2019 | 1025 | 2019 |
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci PL De Jager, X Jia, J Wang, PIW De Bakker, L Ottoboni, NT Aggarwal, ... Nature genetics 41 (7), 776-782, 2009 | 1016 | 2009 |
Interleukin 7 receptor α chain (IL7R) shows allelic and functional association with multiple sclerosis SG Gregory, S Schmidt, P Seth, JR Oksenberg, J Hart, A Prokop, ... Nature genetics 39 (9), 1083-1091, 2007 | 842 | 2007 |
Genome-wide analyses identify KIF5A as a novel ALS gene A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ... Neuron 97 (6), 1268-1283. e6, 2018 | 647 | 2018 |
The fine-scale genetic structure of the British population S Leslie, B Winney, G Hellenthal, D Davison, A Boumertit, T Day, K Hutnik, ... Nature 519 (7543), 309-314, 2015 | 561 | 2015 |
Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors JS Sutcliffe, RJ Delahanty, HC Prasad, JL McCauley, Q Han, L Jiang, C Li, ... The American Journal of Human Genetics 77 (2), 265-279, 2005 | 505 | 2005 |
Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids R Ramesh, L Kozhaya, K McKevitt, IM Djuretic, TJ Carlson, MA Quintero, ... Journal of Experimental Medicine 211 (1), 89-104, 2014 | 496 | 2014 |
Class II HLA interactions modulate genetic risk for multiple sclerosis L Moutsianas, L Jostins, AH Beecham, AT Dilthey, DK Xifara, M Ban, ... Nature genetics 47 (10), 1107, 2015 | 426* | 2015 |
Reconstructing the population genetic history of the Caribbean A Moreno-Estrada, S Gravel, F Zakharia, JL McCauley, JK Byrnes, ... PLoS genetics 9 (11), e1003925, 2013 | 386 | 2013 |
Genome‐wide meta‐analysis identifies novel multiple sclerosis susceptibility loci NA Patsopoulos, ... Annals of neurology 70 (6), 897-912, 2011 | 369 | 2011 |
IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production LM Maier, CE Lowe, J Cooper, K Downes, DE Anderson, C Severson, ... PLoS Genet 5 (1), e1000322, 2009 | 303 | 2009 |
Meta-analysis of genome-wide association studies identifies 1q22 as a susceptibility locus for intracerebral hemorrhage D Woo, GJ Falcone, WJ Devan, WM Brown, A Biffi, TD Howard, ... The American Journal of Human Genetics 94 (4), 511-521, 2014 | 296 | 2014 |
A genome‐wide association study of autism reveals a common novel risk locus at 5p14. 1 D Ma, D Salyakina, JM Jaworski, I Konidari, PL Whitehead, AN Andersen, ... Annals of human genetics 73 (3), 263-273, 2009 | 283 | 2009 |
CD226 Gly307Ser association with multiple autoimmune diseases JP Hafler, LM Maier, JD Cooper, V Plagnol, A Hinks, MJ Simmonds, ... Genes & Immunity 10 (1), 5-10, 2009 | 267 | 2009 |
The role of the CD58 locus in multiple sclerosis PL De Jager, C Baecher-Allan, LM Maier, AT Arthur, L Ottoboni, ... Proceedings of the National Academy of Sciences 106 (13), 5264-5269, 2009 | 246 | 2009 |