Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment. R Coulombe, P Grochulski, J Sivaraman, R Menard, JS Mort, M Cygler The EMBO journal 15 (20), 5492-5503, 1996 | 462 | 1996 |
Linkers in the structural biology of protein–protein interactions VP Reddy Chichili, V Kumar, J Sivaraman Protein science 22 (2), 153-167, 2013 | 452 | 2013 |
Inhibition of bacterial cell division protein FtsZ by cinnamaldehyde P Domadia, S Swarup, A Bhunia, J Sivaraman, D Dasgupta Biochemical pharmacology 74 (6), 831-840, 2007 | 331 | 2007 |
Berberine targets assembly of Escherichia coli cell division protein FtsZ PN Domadia, A Bhunia, J Sivaraman, S Swarup, D Dasgupta Biochemistry 47 (10), 3225-3234, 2008 | 290 | 2008 |
Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism K Thangavelu, CQ Pan, T Karlberg, G Balaji, M Uttamchandani, V Suresh, ... Proceedings of the National Academy of Sciences 109 (20), 7705-7710, 2012 | 247 | 2012 |
Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion M Cygler, J Sivaraman, P Grochulski, R Coulombe, AC Storer, JS Mort Structure 4 (4), 405-416, 1996 | 242 | 1996 |
Structural basis for the inhibition mechanism of human cystathionine γ-lyase, an enzyme responsible for the production of H2S Q Sun, R Collins, S Huang, L Holmberg-Schiavone, GS Anand, CH Tan, ... Journal of Biological Chemistry 284 (5), 3076-3085, 2009 | 229 | 2009 |
Mechanism for controlling the dimer-monomer switch and coupling dimerization to catalysis of the severe acute respiratory syndrome coronavirus 3C-like protease J Shi, J Sivaraman, J Song Journal of virology 82 (9), 4620-4629, 2008 | 174 | 2008 |
Dimerization of hepatitis E virus capsid protein E2s domain is essential for virus–host interaction S Li, X Tang, J Seetharaman, C Yang, Y Gu, J Zhang, H Du, JWK Shih, ... PLoS pathogens 5 (8), e1000537, 2009 | 170 | 2009 |
Two-component PhoB-PhoR regulatory system and ferric uptake regulator sense phosphate and iron to control virulence genes in type III and VI secretion systems of Edwardsiella tarda S Chakraborty, J Sivaraman, KY Leung, YK Mok Journal of Biological Chemistry 286 (45), 39417-39430, 2011 | 149 | 2011 |
Structural basis for the neutralization and genotype specificity of hepatitis E virus X Tang, C Yang, Y Gu, C Song, X Zhang, Y Wang, J Zhang, CL Hew, S Li, ... Proceedings of the National Academy of Sciences 108 (25), 10266-10271, 2011 | 140 | 2011 |
Crystal structures of major envelope proteins VP26 and VP28 from white spot syndrome virus shed light on their evolutionary relationship X Tang, J Wu, J Sivaraman, CL Hew Journal of virology 81 (12), 6709-6717, 2007 | 128 | 2007 |
Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine J Sivaraman, DK Nägler, R Zhang, R Ménard, M Cygler Journal of molecular biology 295 (4), 939-951, 2000 | 121 | 2000 |
Structural basis for the active site inhibition mechanism of human kidney-type glutaminase (KGA) K Thangavelu, QY Chong, BC Low, J Sivaraman Scientific reports 4 (1), 3827, 2014 | 118 | 2014 |
Three-Dimensional Structure of 2-Amino-3-ketobutyrate CoA Ligase from Escherichia coli Complexed with a PLP−Substrate Intermediate: Inferred Reaction … A Schmidt, J Sivaraman, Y Li, R Larocque, JARG Barbosa, C Smith, ... Biochemistry 40 (17), 5151-5160, 2001 | 113 | 2001 |
Specificity Determinants of Human Cathepsin S Revealed by Crystal Structures of Complexes, TA Pauly, T Sulea, M Ammirati, J Sivaraman, DE Danley, MC Griffor, ... Biochemistry 42 (11), 3203-3213, 2003 | 102 | 2003 |
Structure and Evolutionary Origin of Ca2+-Dependent Herring Type II Antifreeze Protein Y Liu, Z Li, Q Lin, J Kosinski, J Seetharaman, JM Bujnicki, J Sivaraman, ... PLoS One 2 (6), e548, 2007 | 101 | 2007 |
Structural and Functional Characterization of a Novel Homodimeric Three-finger Neurotoxin from the Venom of Ophiophagus hannah (King Cobra)*♦ A Roy, X Zhou, MZ Chong, D D'hoedt, CS Foo, N Rajagopalan, ... Journal of Biological Chemistry 285 (11), 8302-8315, 2010 | 99 | 2010 |
The occluding loop in cathepsin B defines the pH dependence of inhibition by its propeptide O Quraishi, DK Nägler, T Fox, J Sivaraman, M Cygler, JS Mort, AC Storer Biochemistry 38 (16), 5017-5023, 1999 | 98 | 1999 |
Design of noncovalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides SF Chowdhury, J Sivaraman, J Wang, G Devanathan, P Lachance, H Qi, ... Journal of medicinal chemistry 45 (24), 5321-5329, 2002 | 97 | 2002 |