| Gut microbiota from twins discordant for obesity modulate metabolism in mice VK Ridaura, JJ Faith, FE Rey, J Cheng, AE Duncan, AL Kau, NW Griffin, ... Science 341 (6150), 1241214, 2013 | 4390 | 2013 |
| A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance CB Newgard, J An, JR Bain, MJ Muehlbauer, RD Stevens, LF Lien, ... Cell metabolism 9 (4), 311-326, 2009 | 3447 | 2009 |
| Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1 JC Yoon, P Puigserver, G Chen, J Donovan, Z Wu, J Rhee, G Adelmant, ... Nature 413 (6852), 131-138, 2001 | 2296 | 2001 |
| Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance TR Koves, JR Ussher, RC Noland, D Slentz, M Mosedale, O Ilkayeva, ... Cell metabolism 7 (1), 45-56, 2008 | 2203 | 2008 |
| SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation MD Hirschey, T Shimazu, E Goetzman, E Jing, B Schwer, DB Lombard, ... Nature 464 (7285), 121-125, 2010 | 1825 | 2010 |
| Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor T Shimazu, MD Hirschey, J Newman, W He, K Shirakawa, N Le Moan, ... Science 339 (6116), 211-214, 2013 | 1749 | 2013 |
| Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes DM Muoio, CB Newgard Nature reviews Molecular cell biology 9 (3), 193-205, 2008 | 1652 | 2008 |
| Interplay between lipids and branched-chain amino acids in development of insulin resistance CB Newgard Cell metabolism 15 (5), 606-614, 2012 | 1111 | 2012 |
| Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and-independent glucose-stimulated insulin secretion. HE Hohmeier, H Mulder, G Chen, R Henkel-Rieger, M Prentki, ... Diabetes 49 (3), 424-430, 2000 | 1060 | 2000 |
| Direct antidiabetic effect of leptin through triglyceride depletion of tissues M Shimabukuro, K Koyama, G Chen, MY Wang, F Trieu, Y Lee, ... Proceedings of the National Academy of Sciences 94 (9), 4637-4641, 1997 | 927 | 1997 |
| SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome MD Hirschey, T Shimazu, E Jing, CA Grueter, AM Collins, B Aouizerat, ... Molecular cell 44 (2), 177-190, 2011 | 875 | 2011 |
| Hyperlipidemic effects of dietary saturated fats mediated through PGC-1β coactivation of SREBP J Lin, R Yang, PT Tarr, PH Wu, C Handschin, S Li, W Yang, L Pei, M Uldry, ... Cell 120 (2), 261-273, 2005 | 807 | 2005 |
| Gut bacteria that prevent growth impairments transmitted by microbiota from malnourished children LV Blanton, MR Charbonneau, T Salih, MJ Barratt, S Venkatesh, ... Science 351 (6275), aad3311, 2016 | 770 | 2016 |
| Cafeteria diet is a robust model of human metabolic syndrome with liver and adipose inflammation: comparison to high‐fat diet BP Sampey, AM Vanhoose, HM Winfield, AJ Freemerman, ... Obesity 19 (6), 1109-1117, 2011 | 763 | 2011 |
| Metabolic coupling factors in pancreatic beta-cell signal transduction. CB Newgard, JD McGarry Annual review of biochemistry 64, 689-719, 1995 | 750 | 1995 |
| Metabolomics and metabolic diseases: where do we stand? CB Newgard Cell metabolism 25 (1), 43-56, 2017 | 749 | 2017 |
| STZ transport and cytotoxicity: specific enhancement in GLUT2-expressing cells WJ Schnedl, S Ferber, JH Johnson, CB Newgard Diabetes 43 (11), 1326-1333, 1994 | 747 | 1994 |
| Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation VA Gerriets, RJ Kishton, AG Nichols, AN Macintyre, M Inoue, O Ilkayeva, ... The Journal of clinical investigation 125 (1), 194-207, 2015 | 722 | 2015 |
| Bioenergetic analysis of peroxisome proliferator-activated receptor γ coactivators 1α and 1β (PGC-1α and PGC-1β) in muscle cells J St-Pierre, J Lin, S Krauss, PT Tarr, R Yang, CB Newgard, ... Journal of Biological Chemistry 278 (29), 26597-26603, 2003 | 712 | 2003 |
| Use of recombinant adenovirus for metabolic engineering of mammalian cells TC Becker, RJ Noel, WS Coats, AM Gomez-Foix, T Alam, RD Gerard, ... Methods in cell biology 43, 161-189, 1994 | 711 | 1994 |
