| Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice EC Holland, J Celestino, C Dai, L Schaefer, RE Sawaya, GN Fuller Nature genetics 25 (1), 55-57, 2000 | 1135 | 2000 |
| Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis C Dai, L Whitesell, AB Rogers, S Lindquist Cell 130 (6), 1005-1018, 2007 | 991 | 2007 |
| PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo C Dai, JC Celestino, Y Okada, DN Louis, GN Fuller, EC Holland Genes & development 15 (15), 1913-1925, 2001 | 827 | 2001 |
| Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt L Uhrbom, C Dai, JC Celestino, MK Rosenblum, GN Fuller, EC Holland Cancer research 62 (19), 5551-5558, 2002 | 368 | 2002 |
| Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis AH Shih, C Dai, X Hu, MK Rosenblum, JA Koutcher, EC Holland Cancer research 64 (14), 4783-4789, 2004 | 253 | 2004 |
| HSF1: guardian of proteostasis in cancer C Dai, SB Sampson Trends in cell biology 26 (1), 17-28, 2016 | 225 | 2016 |
| MEK guards proteome stability and inhibits tumor-suppressive amyloidogenesis via HSF1 Z Tang, S Dai, Y He, RA Doty, LD Shultz, SB Sampson, C Dai Cell 160 (4), 729-744, 2015 | 178 | 2015 |
| Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis C Dai, S Santagata, Z Tang, J Shi, J Cao, H Kwon, RT Bronson, ... The Journal of clinical investigation 122 (10), 3742-3754, 2012 | 147 | 2012 |
| Sulforaphane activates heat shock response and enhances proteasome activity through up-regulation of Hsp27 N Gan, YC Wu, M Brunet, C Garrido, FL Chung, C Dai, L Mi Journal of Biological Chemistry 285 (46), 35528-35536, 2010 | 145 | 2010 |
| Glioma models C Dai, EC Holland Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1551 (1), M19-M27, 2001 | 134 | 2001 |
| The heat-shock, or HSF1-mediated proteotoxic stress, response in cancer: from proteomic stability to oncogenesis C Dai Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018 | 121 | 2018 |
| p190RhoGAP can act to inhibit PDGF-induced gliomas in mice: a putative tumor suppressor encoded on human chromosome 19q13. 3 RM Wolf, N Draghi, X Liang, C Dai, L Uhrbom, C Eklöf, B Westermark, ... Genes & development 17 (4), 476-487, 2003 | 115 | 2003 |
| Suppression of the HSF 1‐mediated proteotoxic stress response by the metabolic stress sensor AMPK S Dai, Z Tang, J Cao, W Zhou, H Li, S Sampson, C Dai The EMBO journal 34 (3), 275-293, 2015 | 110 | 2015 |
| Astrocytes give rise to oligodendrogliomas and astrocytomas after gene transfer of polyoma virus middle T antigen in vivo EC Holland, Y Li, J Celestino, C Dai, L Schaefer, RA Sawaya, GN Fuller The American journal of pathology 157 (3), 1031-1037, 2000 | 102 | 2000 |
| HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth KH Su, J Cao, Z Tang, S Dai, Y He, SB Sampson, IJ Benjamin, C Dai Nature cell biology 18 (5), 527-539, 2016 | 97 | 2016 |
| Proteotoxic stress of cancer: implication of the heat‐shock response in oncogenesis C Dai, S Dai, J Cao Journal of cellular physiology 227 (8), 2982-2987, 2012 | 92 | 2012 |
| MYC expression promotes the proliferation of neural progenitor cells in culture and in vivo D Fults, C Pedone, C Dai, EC Holland Neoplasia 4 (1), 32-39, 2002 | 87 | 2002 |
| mTORC1 senses stresses: Coupling stress to proteostasis KH Su, C Dai Bioessays 39 (5), 1600268, 2017 | 79 | 2017 |
| Overexpression of c-MYC promotes an undifferentiated phenotype in cultured astrocytes and allows elevated Ras and Akt signaling to induce gliomas from GFAP-expressing cells in mice AB Lassman, C Dai, GN Fuller, AJ Vickers, EC Holland Neuron glia biology 1 (2), 157-163, 2004 | 71 | 2004 |
| The characteristics of astrocytomas and oligodendrogliomas are caused by two distinct and interchangeable signaling formats C Dai, Y Lyustikman, A Shih, X Hu, GN Fuller, M Rosenblum, EC Holland Neoplasia 7 (4), 397-406, 2005 | 70 | 2005 |
